#disease  an impairment of health or a condition of abnormal functioning
  supertype:  #illness__illnes__sickness  impairment of normal physiological function affecting part or all of an organism
  part:  #symptom  #sign.evidence  #syndrome
  subtype:  #aspergillosis__aspergillosi  disease especially in agricultural workers caused by inhalation of Aspergillus spores causing lumps in skin and ears and respiratory organs
  subtype:  #blackwater  any of several human or animal diseases characterized by dark urine resulting from rapid breakdown of red blood cells
  subtype:  #cat_scratch_disease__catscratchdisease  a disease thought to be transmitted to humans by a scratch from a cat
  subtype:  #complication.disease  any disease or disorder that occurs during the course of (or because of) another disease; "bed sores are a common complication in cases of paralysis"
  subtype:  #endemic_disease__endemicdisease__endemic  a disease that is constantly present to a greater or lesser degree in people of a certain class or in people living in a particular location
  subtype:  #enteropathy  a disease of the intestinal tract
     subtype:  #intestinal_obstruction__ileus__ileu  blockage of the intestine (especially the ileum) that prevents the contents of the intestine from passing to the lower bowel
  subtype:  #incompetence  inability of a part or organ to function properly
     subtype:  #hypogonadism  incompetence of the gonads (especially in the male with low testosterone)
     subtype:  #valvular_incompetence  inability of a bodily valve to close completely
  subtype:  #Kawasaki_disease__mucocutaneous_lymph_node_syndrome  an acute disease of young children characterized by a rash and swollen lymph nodes and fever; of unknown cause
  subtype:  #pycnosis__pyknosis  a degenerative state of the cell nucleus
  subtype:  #Marseilles_fever__Kenya_fever__Indian_tick_fever__boutonneuse_fever__boutonneusefever  a disease (common in India and around the Mediterranean area) caused by a rickettsia that is transmitted to humans by a reddish brown tick (ixodid) that lives on dogs and other mammals
  subtype:  #Meniere's_disease  a disease of the inner ear characterized by episodes of dizziness and tinnitus and progressive hearing loss (usually unilateral)
  subtype:  #milk_sickness  caused by consuming milk from cattle suffering from trembles
  subtype:  #mimesis.disease  any disease that shows symptoms characteristic of another disease
  subtype:  #myasthenia_gravis__myasthenia  a chronic progressive disease characterized by chronic fatigue and muscular weakness (especially in the face and neck); caused by a deficiency of acetylcholine at the neuromuscular junctions
  subtype:  #occupational_disease__industrial_disease  disease or disability resulting from conditions of employment (usually from long exposure to a noxious substance or from continuous repetition of certain acts)
  subtype:  #onychosis__onychosi  any disease or disorder of the nails
     subtype:  #onycholysis__onycholysi  separation of a nail from its normal attachment to the nail bed
  subtype:  #rheumatism  any painful disorder of the joints or muscles or connective tissues
  subtype:  #periarteritis_nodosa__periarteritisnodosa__polyarteritis_nodosa__polyarteritisnodosa  a progressive disease of connective tissue that is characterized by nodules along arteries; nodules may block the artery and result in inadequate circulation to the particular area
  subtype:  #periodontal_disease__periodontaldisease__periodontitis__periodontiti  a disease that attacks the gum and bone and around the teeth
     subtype:  #pyorrhea_alveolaris__pyorrhea__pyorrhoea__Riggs'_disease  chronic periodontitis; purulent inflammation of the teeth sockets
        subtype:  #pericementoclasia  pus pocket formation around a tooth
     subtype:  #alveolar_resorption  wasting of the bony socket
     subtype:  #gingivitis  inflammation of the gums
     subtype:  #ulatrophia  recession of the gums
  subtype:  #liver_disease__liverdisease  a disease affecting the liver
     subtype:  #cirrhosis_of_the_liver__cirrhosis__cirrhosi  a chronic disease interfering with the normal functioning of the liver; the major cause is chronic alcoholism
     subtype:  #fatty_liver__fattyliver  yellow discoloration as a result of the accumulation of certain fats (triglycerides) in the liver; can be caused by alcoholic cirrhosis or pregnancy or exposure to certain toxins
     subtype:  #hepatitis__hepatiti  inflammation of the liver caused by a virus or a toxin
        subtype:  #viral_hepatitis__viralhepatiti  hepatitis caused by a virus
           subtype:  #hepatitis_A__infectious_hepatitis  an acute but benign form of viral hepatitis caused by an RNA virus that does not persist in the blood serum and is usually transmitted by ingesting food or drink that is contaiminated with fecal matter
           subtype:  #hepatitis_B__serum_hepatitis  an acute (sometimes fatal) form of viral hepatitis caused by a DNA virus that tends to persist in the blood serum and is transmitted by sexual contact or by transfusion or by ingestion of contaminated blood or other bodily fluids
           subtype:  #hepatitis_C  a viral hepatitis clinically indistinguishable from hepatitis B but caused by a single-stranded RNA virus; usually transmitted by parenteral means (as injection of an illicit drug or blood transfusion or exposure to blood or blood products)
        subtype:  #hepatitis_delta__hepatitisdelta__delta_hepatitis__deltahepatiti  a severe form of hepatitis
     subtype:  #liver_cancer__livercancer__cancer_of_the_liver  malignant neoplastic disease of the liver usually occurring as a metastasis from another cancer; symptoms include loss of appetite and weakness and bloating and jaundice and upper abdominal discomfort
  subtype:  #communicable_disease  a disease that can be communicated from one person to another
     subtype:  #contagious_disease__contagion  any disease easily transmitted by contact
        subtype:  #influenza__flu__grippe  an acute febrile highly contagious viral disease
           subtype:  #Asiatic_flu  influenza caused by the Asian virus that was first isolated in 1957
        subtype:  #measles__rubeola  an acute and highly contagious viral disease marked by distinct red spots followed by a rash; occurs primarily in children
           subtype:  #German_measles__rubella__threedaymeasle__epidemic_roseola  a contagious viral disease that is a milder form of measles lasting three or four days; can be damaging to a fetus during the first trimester
        subtype:  #diphtheria  acute contagious bacterial infection marked by the formation of a false membrane in the throat and other air passages causing difficulty in breathing
        subtype:  #scarlet_fever__scarletfever__scarlatina  an acute communicable disease (usually in children) characterized by fever and a red rash
        subtype:  #pox  a contagious disease characterized by purulent skin eruptions that may leave pock marks
           subtype:  #smallpox__variola  a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scars
           subtype:  #chickenpox__varicella  an acute contagious disease caused by herpes varicella zoster virus; causes a rash of vesicles on the face and body
        subtype:  #Vincent's_angina__Vincent's_infection__trench_mouth  an acute communicable infection of the respiratory tract and mouth marked by ulceration of the mucous membrane
        subtype:  #venereal_disease__VD__social_disease__Cupid's_itch__Cupid's_disease__Venus's_curse__sexually_transmitted_disease  a communicable disease transmitted by sexual intercourse or genital contact
           subtype:  #genital_herpes__herpes_genitalis  an infection caused by herpes simplex virus type 2 (HSV-2) that is usually transmitted by sexual contact; marked by recurrent attacks of painful eruptions on the skin and mucous membranes of the genital area
           subtype:  #gonorrhea__gonorrhoea__clap  a common venereal disease caused by the bacterium Neisseria gonorrhoeae; symptoms are painful urination and pain around the urethra
           subtype:  #granuloma_inguinale__granulomainguinale__granuloma_venereum__granulomavenereum  a venereal disease caused by a bacterium of the genus Calymmatobacterium; characterized by a pimply rash of the skin in the genital and groin region
           subtype:  #syphilis__syph__pox  a common venereal disease caused by the Treponema pallidum spirochete; symptoms change through progressive stages; can be congenital (transmitted through the placenta)
              subtype:  #primary_syphilis  the first stage; characterized by a chancre at the site of infection
              subtype:  #secondary_syphilis  the second stage; characterized by eruptions of the skin and mucous membrane
              subtype:  #tertiary_syphilis  the third stage; characterized by involvement of internal organs especially the brain and spinal cord as well as the heart and liver
              subtype:  #neurosyphilis__neurosyphili  syphilis of the central nervous system
                 subtype:  #tabes_dorsalis__locomotor_ataxia__locomotorataxia  syphilis of the spinal cord characterized by degeneration of sensory neurons and stabbing pains in the trunk and legs and unsteady gait and incontinence and impotence
     subtype:  #infectious_disease  a disease transmitted only by a specific kind of contact
        subtype:  #AIDS__acquired_immune_deficiency_syndrome  a serious (often fatal) disease of the immune system transmitted through blood products especially by sexual contact or contaminated needles
        subtype:  #undulant_fever__brucellosis__Malta_fever__Gibraltar_fever__Rock_fever__Mediterranean_fever  infectious bacterial disease of human beings transmitted by contact with infected animals or infected meat or milk products; characterized by fever and headache
        subtype:  #epidemic_cholera__cholera__Asiatic_cholera__Indian_cholera  an acute intestinal infection caused by ingestion of contaminated water or food
        subtype:  #dengue_fever__dengue__dandy_fever__dandyfever__breakbone_fever  an infectious disease of the tropics transmitted by mosquitoes and characterized by rash and aching head and joints
        subtype:  #dysentery  an infection of the intestines marked by severe diarrhea
           subtype:  #amebic_dysentery__amoebic_dysentery__amoebicdysentery  inflammation of the intestines caused by Endamoeba histolytica; usually acquired by ingesting food or water contaminated with feces; characterized by severe diarrhea
           subtype:  #shigellosis__bacillary_dysentery__bacillarydysentery  an acute infection of the intestine by Shigella bacteria; characterized by diarrhea and fever and abdominal pains
        subtype:  #epidemic_disease  any infectious disease that develops and spreads rapidly to many people
           subtype:  #plague.epidemic_disease__pestilence  any epidemic disease with a high death rate
           subtype:  #plague  a serious (sometimes fatal) infection transmitted by the bite of an infected rat flea (especially bubonic plague)
              subtype:  #bubonic_plague__bubonicplague  plague characterized by delirium and the formation of buboes
                 subtype:  #Black_Death__black_plague__blackplague  the epidemic form of bubonic plague experienced during the Middle Ages when it killed nearly half the people of western Europe
              subtype:  #pneumonic_plague__pneumonicplague  characterized by lung involvement
              subtype:  #septicemic_plague  an especially dangerous form in which infecting organisms invade the bloodstream
           subtype:  #epidemic_pleurodynia__epidemic_myalgia__myosis__diaphragmatic_pleurisy__diaphragmaticpleurisy__Bornholm_disease  an acute infectious disease occurring in epidemic form and featuring paroxysms of pain (usually in the chest)
        subtype:  #hepatitis__hepatiti  inflammation of the liver caused by a virus or a toxin
        subtype:  #herpes  viral diseases causing eruptions of the skin or mucous membrane
           subtype:  #herpes_simplex  an infection caused by the herpes simples virus; affects the skin and nervous system; produces small temporary (but sometimes painful) blisters on the skin and mucous membranes
              subtype:  #oral_herpes__herpes_labialis__cold_sore__fever_blister__feverblister  caused by herpes simplex virus type 1 (HSV-1)
              subtype:  #genital_herpes__herpes_genitalis  an infection caused by herpes simplex virus type 2 (HSV-2) that is usually transmitted by sexual contact; marked by recurrent attacks of painful eruptions on the skin and mucous membranes of the genital area
           subtype:  #herpes_zoster__zoster__shingles  eruptions along a nerve path often accompanied by severe neuralgia
        subtype:  #infectious_mononucleosis__mononucleosis__mononucleosi__mono__glandular_fever__glandularfever__kissing_disease__kissingdisease  an acute disease characterized by fever and swollen lymph nodes and an abnormal increase of mononuclear leucocytes or monocytes in the bloodstream; not highly contagious; some believe it can be transmitted by kissing
        subtype:  #Lassa_fever  a serious contagious viral disease of central western Africa; characterized by fever and inflammation and muscular pains and difficulty swallowing
        subtype:  #leprosy__hansen'sdisease  chronic granulomatous communicable disease occurring in tropical and subtropical regions; characterized by inflamed nodules beneath the skin and wasting of body parts; caused by the bacillus Mycobacterium leprae
           subtype:  #tuberculoid_leprosy  leprosy characterized by tumors in the skin and cutaneous nerves
           subtype:  #lepromatous_leprosy  a very serious form of leprosy characterized by lesions that spread over much of the body and affecting many systems of the body
        subtype:  #listeriosis__listeriosi  an infectious disease common to many animals and occasionally transmitted to humans (especially to newborn or immunosuppressed persons)
        subtype:  #lymphogranuloma_venereum__lymphogranulomavenereum__LGV__lymphopathia_venereum  infectious disease caused by a species of chlamydia bacterium; transmitted by sexual contact; characterized by genital lesions and swelling of lymph nodes in the groin
        subtype:  #meningitis  infectious disease characterized by inflammation of the meninges (the tissues that surround the brain or spinal cord) caused by a bacterial infection; symptoms include headache and stiff neck and fever and nausea
           subtype:  #cerebrospinal_meningitis__epidemic_meningitis__brain_fever__brainfever__cerebrospinal_fever__cerebrospinalfever  meningitis caused by bacteria and often fatal
           subtype:  #leptomeningitis  inflammation of the leptomeninges
        subtype:  #mumps__mump__epidemic_parotitis  an acute contagious viral disease characterized by fever and by swelling of the parotid glands
        subtype:  #paratyphoid_fever__paratyphoidfever__paratyphoid  any of a variety of infectious intestinal diseases resembling typhoid fever
        subtype:  #acute_anterior_poliomyelitis__poliomyelitis__poliomyeliti__polio__infantileparalysi  an acute viral disease marked by inflammation of nerve cells of the brain stem and spinal cord
        subtype:  #ratbite_fever__ratbitefever  either of two infectious diseases transmitted to humans by the bite of a rat or mouse; characterized by fever and headache and nausea and skin eruptions
           subtype:  #Haverhill_fever  the form of ratbite fever occurring in the United States
           subtype:  #sodoku__spirillum_fever  the form of ratbite fever occurring in the Far East
        subtype:  #rickettsial_disease__rickettsialdisease__rickettsiosis__rickettsiosi  infectious disease caused by ticks or mites or body lice infected with rickettsial bacteria
           subtype:  #typhus_fever__typhus  rickettsial disease transmitted by body lice and characterized by skin rash and high fever
              subtype:  #murine_typhus__rat_typhus__urban_typhus__endemic_typhus  acute infection caused by rickettsia and transmitted by the bite of an infected flea; characterized by fever and chills and muscle aches and a rash
           subtype:  #spotted_fever__spottedfever  any of several severe febrile diseases characterized by skin rashes or spots on the skin
              subtype:  #Rocky_Mountain_spotted_fever__mountain_fever__tick_fever  caused by rickettsial bacteria and transmitted by wood ticks
           subtype:  #Q_fever  an acute disease resembling influenza
           subtype:  #ricketsialpox  mild infectious rickettsial disease caused by a bacterium of the genus Rickettsia transmitted to humans by the bite a mite that lives on rodents; characterized by chills and fever and headache and skin lesions that resemble chickenpox
           subtype:  #trench_fever  marked by pain in muscles and joints and transmitted by lice
           subtype:  #tsutsugamushi_disease__tsutsugamushidisease__scrub_typhus  transmitted by larval mites and widespread in Asia
        subtype:  #relapsing_fever__recurrent_fever  marked by recurring high fever and transmitted by the bite of infected lice or ticks; characterized by episodes of high fever and chills and headache and muscle pain and nausea that recur every week or ten days for several months
        subtype:  #rheumatic_fever  a severe disease chiefly of children and characterized by painful inflammation of the joints and frequently damage to the heart valves
        subtype:  #miliary_fever__miliaryfever__sweating_sickness  epidemic in the 15th and 16th centuries and characterized by profuse sweating and high mortality
        subtype:  #tuberculosis__TB__T.B.  infection transmitted by inhalation or ingestion of tubercle bacilli and manifested in fever and small lesions (usually in the lungs but in various other parts of the body in acute stages)
           subtype:  #Pott's_disease  TB of the spine with destruction of vertebrae resulting in curvature of the spine
           subtype:  #miliary_tuberculosis  acute tuberculosis characterized by the appearance of tiny tubercles on one or more organs of the body (presumably resulting from tubercle bacilli being spread in the bloodstream)
           subtype:  #pulmonary_tuberculosis__consumption__phthisi__wasting_disease__wastingdisease__white_plague__whiteplague  involving the lungs with progressive wasting of the body
           subtype:  #scrofula__struma__king's_evil  a form of tuberculosis characterized by swellings of the lymphatic glands
           subtype:  #lupus_vulgaris  tuberculosis of the skin; appears first on the face and heals slowly leaving deep scars
        subtype:  #typhoid_fever__typhoidfever__typhoid__enteric_fever__entericfever  serious infection marked by intestinal inflammation and ulceration; caused by Salmonella typhosa ingested with food or water
        subtype:  #whooping_cough__pertussis__pertussi  a disease of the respiratory mucous membrane
        subtype:  #yaws__frambesia__framboesia  an infectious tropical disease resembling syphilis in its early stages; marked by red skin eruptions and ulcerating lesions
        subtype:  #yellow_fever__yellow_jack__black_vomit__blackvomit  caused by a virus transmitted by a mosquito
     subtype:  #common_cold__cold  a mild viral infection involving the nose and respiratory passages (but not the lungs); "will they never find a cure for the common cold?"
        subtype:  #head_cold  a common cold affecting the nasal passages and resulting in congestion and sneezing and headache
  subtype:  #exanthema_subitum__exanthemasubitum__roseola_infantum__roseolainfantum__roseola_infantilis__pseudorubella  a viral disease of infants and young children; characterized by abrupt high fever and mild sore throat; a few days later there is a faint pinkish rash that lasts for a few hours to a few days
  subtype:  #respiratory_disease__respiratorydisease__respiratory_disorder__respiratorydisorder  a disease affecting the respiratory system
     subtype:  #influenza__flu__grippe  an acute febrile highly contagious viral disease
     subtype:  #whooping_cough__pertussis__pertussi  a disease of the respiratory mucous membrane
     subtype:  #common_cold__cold  a mild viral infection involving the nose and respiratory passages (but not the lungs); "will they never find a cure for the common cold?"
     subtype:  #bronchial_asthma__bronchialasthma__asthma__asthma_attack  respiratory disorder characterized by wheezing; usually of allergic origin
        subtype:  #status_asthmaticus  a prolonged and severe asthma attack that does not respond to standard treatment
     subtype:  #bronchitis  inflammation of the membranes lining the bronchial tubes
        subtype:  #bronchiolitis__bronchioliti  inflammation of the membranes lining the bronchioles
        subtype:  #chronic_bronchitis  a form of bronchitis characterized by excess production of sputum leading to a chronic cough and obstruction of air flow
           subtype:  #chronic_obstructive_pulmonary_disease__chronicobstructivepulmonarydisease  a nonreversible lung disease that is a combination of emphysema and chronic bronchitis; usually patients have been heavy cigarette smokers
     subtype:  #pulmonary_emphysema__pulmonaryemphysema__emphysema  an abnormal condition of the lungs marked by decreased respiratory function; associated with smoking or chronic bronchitis or old age
        subtype:  #chronic_obstructive_pulmonary_disease__chronicobstructivepulmonarydisease  a nonreversible lung disease that is a combination of emphysema and chronic bronchitis; usually patients have been heavy cigarette smokers
     subtype:  #pneumonia  respiratory disease characterized by inflammation of the lung parenchyma (excluding the bronchi) with congestion caused by viruses or bacteria or irritants
        subtype:  #bronchopneumonia__bronchial_pneumonia  pneumonia characterized by acute inflammation of the walls of the bronchioles
           subtype:  #aspiration_pneumonia  bronchopneumonia resulting from foreign material (usually vomit or food particles) entering the bronchi
        subtype:  #lobar_pneumonia  pneumonia affecting one or more lobes of the lung; commonly due to streptococcal infection
           subtype:  #double_pneumonia  lobar pneumonia involving both lungs
           subtype:  #Legionnaire's_disease  acute (sometimes fatal) lobar pneumonia caused by bacteria of a kind first recognized after an outbreak of the disease at an American Legion convention in Philadelphia in 1976; characterized by fever and muscle and chest pain and headache and chills and a dry cough
        subtype:  #pneumococcal_pneumonia  pneumonia caused by bacteria of the genus pneumococcus
        subtype:  #pneumocytosis__pneumocytosi__pneumocystis_pneumonia__pneumocystis_carinii_pneumonia__interstitial_plasma_cell_pneumonia  pneumonia occurring in infants or in persons with impaired immune systems (as AIDS victims)
        subtype:  #pleuropneumonia  pleurisy and pneumonia
        subtype:  #viral_pneumonia__viralpneumonia  pneumonia caused by a virus
     subtype:  #primary_atypical_pneumonia__atypical_pneumonia__mycoplasmal_pneumonia__mycoplasmalpneumonia  an acute respiratory disease marked by high fever and coughing; caused by mycoplasma; primarily affecting children and young adults
        subtype:  #parrot_fever__psittacosis__psittacosi__ornithosis  an atypical pneumonia caused by a rickettsia microorganism and transmitted to humans from infected birds
     subtype:  #interstitial_pneumonia  chronic lung disease affecting the interstitial tissue of the lungs
     subtype:  #pneumoconiosis__pneumonoconiosis  chronic respiratory disease caused by inhaling metallic or mineral particles
        subtype:  #anthracosis__anthracosi__black_lung__blacklung__blacklungdisease__coal_miner's_lung  lung disease caused by inhaling coal dust
        subtype:  #asbestosis  lung disease caused by inhaling asbestos particles
        subtype:  #siderosis__siderosi  fibrosis of the lung caused by iron dust; occurs among welders and other metal workers
        subtype:  #silicosis__silicosi  a lung disease caused by inhaling particles of silica or quartz or slate
     subtype:  #respiratory_distress_syndrome_of_the_newborn__respiratory_distress_syndrome__hyaline_membrane_disease  an acute lung disease of the newborn (especially the premature newborn); lungs cannot expand because of a wetting agent is lacking; characterized by rapid shallow breathing and cyanosis and the formation of a glassy hyaline membrane over the alveoli
  subtype:  #genetic_disease__geneticdisease__genetic_disorder__geneticdisorder__genetic_abnormality__geneticabnormality__genetic_defect__geneticdefect__congenital_disease__inherited_disease__inheriteddisease__inherited_disorder__inheriteddisorder__hereditary_disease__hereditary_condition  a disease or disorder that is inherited genetically
     subtype:  #achondroplasia__achondroplasty__osteosclerosis_congenita__chondrodystrophy  an inherited skeletal disorder beginning before birth; cartilage is converted to bone resulting in dwarfism
     subtype:  #abetalipoproteinemia  a rare inherited disorder of fat metabolism; characterized by severe deficiency of beta-lipoproteins and abnormal red blood cells (acanthocytes) and abnormally low cholesterol levels
     subtype:  #cystic_fibrosis__fibrocystic_disease_of_the_pancreas__pancreatic_fibrosis__mucoviscidosis  a congenital disease in which the pancreas and lungs and intestines become clogged with mucus
     subtype:  #inborn_error_of_metabolism  any of a number of diseases in which an inherited defect (usually a missing or inadequate enzyme) results in an abnormality of metabolism
        subtype:  #galactosemia  a genetic disease (autosomal recessive) in which an enzyme needed to metabolize galactose is deficient or absent; typically develops shortly after birth
        subtype:  #lysinemia  an inborn error of metabolism in which the lack of certain enzymes leads to an inability to metabolize the amino acid lysine; characterized by muscular weakness and mental retardation
        subtype:  #Niemann-Pick_disease  a disorder of lipid metabolism that is inherited as an autosomal recessive trait
        subtype:  #Tay-Sachs_disease__Tay-Sachs__Sachs_disease__infantile_amaurotic_idiocy__infantileamauroticidiocy  a hereditary disorder of lipid metabolism occuring most frequently in individuals of E European Jewish descent; accumulation of lipids in nervous tissue results in death in early childhood
        subtype:  #phenylketonuria__PKU  a genetic disorder of metabolism; lack of the enzyme needed to turn phenylalanine into tyrosine results in an accumulation of phenylalanine in the body fluids which causes various degrees of mental deficiency
     subtype:  #Hirschsprung's_disease__congenital_megacolon  congenital condition in which the colon does not have the normal network of nerves; there is little urge to defecate so the feces accumulate and cause megacolon
     subtype:  #mucopolysaccharidosis__mucopolysaccharidosi  any of a group of genetic disorders involving a defect in the metabolism of mucopolysaccharides resulting in greater than normal levels of mucopolysaccharides in tissues
        subtype:  #Hurler's_syndrome__Hurler's_disease__gargoylism__dysostosis_multiplex__lipochondrodystrophy  hereditary disease (autosomal recessive) consisting of an error is mucopolysaccharide metabolism; characterized by severe abnormalities in development of skeletal cartilage and bone and mental retardation
     subtype:  #hyperbetalipoproteinemia  a genetic disorder characterized by high levels of beta-lipoproteins and cholesterol; can lead to atherosclerosis at an early age
     subtype:  #ichthyosis  any of several congenital diseases in which the skin is fishlike (dry and scaly)
     subtype:  #maple_syrup_urine_disease__maplesyrupurinedisease__branched_chain_ketoaciduria  an inherited disorder of metabolism in which the urine has a odor characteristic of maple syrup; if untreated it can lead to mental retardation and death in early childhood
     subtype:  #McArdle's_disease  an inherited disease in which abnormal amounts of glycogen accumulate in skeletal muscle; results in weakness and cramping
     subtype:  #muscular_dystrophy__dystrophy  any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles
        subtype:  #Duchenne's_muscular_dystrophy__pseudohypertrophic_dystrophy  the most common form of muscular dystrophy; X-linked recessive (affecting only males)
        subtype:  #limb-girdle_muscular_dystrophy  an autosomal recessive form of muscular dystrophy characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle
        subtype:  #myotonic_muscular_dystrophy__myotonia_atrophica__Steinert's_disease  a severe form of muscular dystrophy marked by facial weakness and drooping eyelids and difficult speech and difficulty with the hands that spreads to the arms and shoulders and legs and hips
     subtype:  #oligodactyly  congenital condition in which some fingers or toes are missing
     subtype:  #oligodontia  congenital condition in which some of the teeth are missing
     subtype:  #otosclerosis  hereditary disorder in which ossification of the labyrinth of the inner ear causes tinnitus and eventual deafness
     subtype:  #autosomal_dominant_disease__autosomal_dominant_disorder  a disease caused by a dominant mutant gene on an autosome
        subtype:  #Huntington's_chorea__Huntington's_disease  hereditary; develops in adulthood and ends in dementia
        subtype:  #malignant_hyperthermia__malignanthyperthermia  hereditary condition in which certain anesthetics (e.g., halothane) cause high body temperatures and muscle rigidity
        subtype:  #Marfan's_syndrome  an autosomal dominant disease characterized by elongated bones (especially of limbs and digits) and abnormalities of the eyes and circulatory system
        subtype:  #neurofibromatosis__neurofibromatosi__von_Recklinghausen's_disease  autosomal dominant disease characterized by numerous neurofibromas and by spots on the skin and often by developmental abnormalities
        subtype:  #osteogenesis_imperfecta  autosomal dominant disorder of connective tissue characterized by brittle bones that fracture easily
     subtype:  #autosomal_recessive_disease__autosomalrecessivedisease__autosomal_recessive_defect__autosomalrecessivedefect  a disease caused by the presence of two recessive mutant genes on an autosome
        subtype:  #limb-girdle_muscular_dystrophy  an autosomal recessive form of muscular dystrophy characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle
        subtype:  #Niemann-Pick_disease  a disorder of lipid metabolism that is inherited as an autosomal recessive trait
        subtype:  #Tay-Sachs_disease__Tay-Sachs__Sachs_disease__infantile_amaurotic_idiocy__infantileamauroticidiocy  a hereditary disorder of lipid metabolism occuring most frequently in individuals of E European Jewish descent; accumulation of lipids in nervous tissue results in death in early childhood
        subtype:  #thrombasthenia  a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results
        subtype:  #tyrosinemia  autosomal recessive defect in tyrosine metabolism resulting in liver and kidney disturbances and mental retardation
        subtype:  #Werdnig-Hoffman_disease  autosomal recessive disease in which the degeneration of spinal nerve cells and brain nerve cells leads to atrophy of skeletal muscles and flaccid paralysis; death usually occurs in early childhood
     subtype:  #Fanconi's_anemia__Fanconi's_anaemia__congenital_pancytopenia  a rare congenital anemia characterized by pancytopenia and hypoplasia of the bone marrow
     subtype:  #sickle-cell_anemia__sickle-cell_anaemia__sickle-cell_disease__crescent-cell_anemia__crescent-cell_anaemia__drepanocytic_anemia__drepanocytic_anaemia  a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape
     subtype:  #Spielmeyer-Vogt_disease__juvenile_amaurotic_idiocy  a congenital progressive disorder of lipid metabolism having an onset at age 5 and characterized by blindness and dementia and early death
     subtype:  #congenital_afibrinogenemia  a rare congenital disorder of blood coagulation in which no fibrinogen is found in the blood plasma
     subtype:  #osteopetrosis__Albers-Schonberg_disease__marble_bones_disease  an inherited disorder characterized by an increase in bone density; in severe forms the bone marrow cavity may be obliterated
     subtype:  #nevoid_elephantiasis__pachyderma  thickening of the skin (usually unilateral on an extremity) caused by congenital enlargement of lymph vessel and lymph vessel obstruction
     subtype:  #dwarfism__nanism  a genetic abnormality resulting in short stature
        subtype:  #pycnodysostosis__pycnodysostosi  a form of dwarfism accompanied by fragile bones and bad teeth
     subtype:  #lactose_intolerance__lactoseintolerance__lactase_deficiency__lactasedeficiency__milk_intolerance  congenital disorder consisting of an inability to digest milk and milk products; absence or deficiency of lactase results in an inability to hydrolyze lactose
     subtype:  #porphyria  a genetic abnormality of metabolism causing abdominal pains and mental confusion
     subtype:  #hepatolenticular_degeneration__Wilson's_disease  a rare inherited disorder of copper metabolism; copper accumulates in the liver and then in the red blood cells and brain
  subtype:  #inflammatory_disease  a disease characterized by inflammation
     subtype:  #necrotizing_enterocolitis__necrotizingenterocoliti__nec  an acute inflammatory disease occurring in the intestines of premature infants; necrosis of intestinal tissue may follow
     subtype:  #gastroenteritis__stomach_flu__intestinal_flu  inflammation of the stomach and intestines; can be caused by Salmonella enteritidis
        subtype:  #cholera_infantum__cholerainfantum  often fatal form of gastroenteritis occurring in children; not true cholera but having similar symptoms
     subtype:  #pelvic_inflammatory_disease__PID  inflammation of the female pelvic organs (especially the Fallopian tubes) caused by infection by any of several microorganisms (chiefly gonococci and chlamydia); symptoms are abdominal pain and fever and foul-smelling vaginal discharge
     subtype:  #empyema  a collection of pus in a body cavity (especially in the lung cavity)
        subtype:  #purulent_pleurisy  a collection of pus in the lung cavity
     subtype:  #pleurisy  inflammation of the pleura of the lungs (especially the parietal layer)
        subtype:  #purulent_pleurisy  a collection of pus in the lung cavity
        subtype:  #pleuropneumonia  pleurisy and pneumonia
     subtype:  #sore_throat__pharyngitis__raw_throat__rawthroat  inflammation of the fauces and pharynx
        subtype:  #streptococcal_sore_throat__strep_throat__strepthroat__streptococcustonsiliti__septic_sore_throat__throat_infection  an infection of the oral pharynx and tonsils by streptococcus
     subtype:  #angina  any disease of the throat or fauces marked by spasmodic attacks of intense suffocative pain
        subtype:  #Vincent's_angina__Vincent's_infection__trench_mouth  an acute communicable infection of the respiratory tract and mouth marked by ulceration of the mucous membrane
        subtype:  #quinsy__peritonsillar_abscess__peritonsillarabsces  a painful pus-filled inflammation of the tonsils and surrounding tissues; usually a complication of tonsillitis
        subtype:  #croup__spasmodic_laryngitis  a disease of infants and young children; harsh coughing and hoarseness and fever and difficult breathing
     subtype:  #arthritis__arthriti  inflammation of a joint or joints
        subtype:  #rheumatoid_arthritis__atrophic_arthritis__rheumatism  a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
           subtype:  #psoriatic_arthritis  a form of rheumatoid arthritis usually affecting fingers and toes and associated with psoriasis
           subtype:  #Still's_disease__juvenile_rheumatoid_arthritis  a form of rheumatoid arthritis that affects children; large joints become inflamed and bone growth may be retarded
        subtype:  #osteoarthritis__degenerative_arthritis__degenerative_joint_disease  chronic breakdown of cartilage in the joints; the most common form of arthritis occurring usually after middle age
        subtype:  #gout__gouty_arthritis__goutyarthriti__urarthritis__urarthriti  a painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints
        subtype:  #spondylarthritis  arthritis that affects one or more of the intervertebral joints in the spine
     subtype:  #acne  an inflammatory disease involving the sebaceous glands of the skin; characterized by papules or pustules or comedones
        subtype:  #acne_rosacea__rosacea  a skin disease of adults (more often women) in which blood vessels of the face enlarge resulting in a flushed appearance
        subtype:  #acne_vulgaris  the most common form of acne; usually affects people from puberty to young adulthood
     subtype:  #aspiration_penumonia  inflammation of the lungs caused by inhaling or choking on vomitus; may occur during unconsciousness (anesthesia or drunkenness or seizure or cardiac arrest)
     subtype:  #urinary_tract_infection__urinarytractinfection  any infection of any of the organs of the urinary tract
        subtype:  #cystitis  inflammation of the urinary bladder and ureters
        subtype:  #pyelonephritis  inflammation of the kidney and its pelvis caused by bacterial infection
           subtype:  #acute_pyelonephritis  pyelonephritis resulting from the spread of a bladder infection
           subtype:  #chronic_pyelonephritis  pyelonephritis that develops slowly and can lead to renal failure if untreated; often associated with a kidney stone or with narrowing of the urinary passageways
        subtype:  #urethritis  inflammation of the urethra; results in painful urination
           subtype:  #nongonococcal_urethritis__NGU  sexually transmitted urethritis (usually caused by chlamydia)
           subtype:  #nonspecific_urethritis__NSU  inflammation of the urethra of unknown cause
  subtype:  #autoimmune_disease__autoimmune_disorder  any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
     subtype:  #Type_I_diabetes__insulin-dependent_diabetes_mellitus__IDDM__juvenile-onset_diabetes__juvenile_diabetes__growth-onset_diabetes__ketosis-prone_diabetes__ketoacidosis-prone_diabetes__autoimmune_diabetes  severe diabetes mellitus with an early onset; characterized by polyuria and excessive thirst and increased appetite and weight loss and episodic ketoacidosis; diet and insulin injections are required to control the disease
     subtype:  #rheumatoid_arthritis__atrophic_arthritis__rheumatism  a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
     subtype:  #ankylosing_spondylitis__Marie-Strumpell_disease__rheumatoid_spondylitis  a chronic form of spondylitis primarily in males and marked by impaired mobility of the spine; sometimes leads to ankylosis
     subtype:  #discoid_lupus_erythematosus__DLE  a chronic skin disease occurring primarily in women between the ages of 20 and 40; characterized by an eruption of red lesions over the cheeks and bridge of the nose
     subtype:  #Hashimoto's_disease  autoimmune disorder of the thyroid gland; most common in middle-aged women
     subtype:  #lupus_erythematosus__lupuserythematosu__LE  a chronic inflammatory collagen disease affecting connective tissue (skin or joints)
     subtype:  #scleroderma__dermatosclerosis  an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin
        subtype:  #morphea  localized scleroderma
     subtype:  #idiopathic_thrombocytopenic_purpura__thrombocytopenic_purpura__purpura_hemorrhagica__purpurahemorrhagica__Werlhof's_disease  purpura associated with a reduction in circulating blood platelets which can result from a variety of factors
  subtype:  #deficiency_disease  any disease caused by a lack of an essential nutrient (as a vitamin or mineral)
     subtype:  #malnutrition  a state of poor nutrition; can result from insufficient or excessive or unbalanced diet or from inability to absorb foods
        subtype:  #avitaminosis__hypovitaminosis__hypovitaminosi  any of several diseases caused by deficiency of one or more vitamins
           subtype:  #beriberi  avitaminosis caused by lack of thiamine (vitamin B1)
              subtype:  #kakke_disease  the endemic form of beriberi
           subtype:  #pellagra__Alpine_scurvy__mal_de_la_rosa__mal_rosso__malrosso__maidism__Saint_Ignatius'_itch  a disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin); characterized by gastrointestinal disturbances and erythema and nervous or mental disorders; may be caused by malnutrition or alcoholism or other nutritional impairments
           subtype:  #rickets__rachitis  childhood disease caused by deficiency of vitamin D and sunlight associated with impaired metabolism of calcium and phosphorus
           subtype:  #scurvy  a condition caused by deficiency of ascorbic acid (vitamin C)
           subtype:  #nyctalopia__night_blindness__nightblindnes__moon_blindness  inability to see clearly in dim light; due to a deficiency of vitamin A or to a retinal disorder
        subtype:  #kwashiorkor  severe malnutrition in children resulting from a diet excessively high in carbohydrates and low in protein
        subtype:  #marasmus  extreme malnutrition and emaciation (especially in children); can result from inadequate intake of food or from malabsorption or metabolic disorders
     subtype:  #zinc_deficiency  a deficiency caused by inadequate zinc in the diet or by liver disease or cystic fibrosis or other diseases
  subtype:  #fibrocystic_breast_disease__fibrocystic_disease_of_the_breast__cystic_breast_disease__cystic_mastitis  the presence of one or more cysts in a breast
  subtype:  #goiter__goitre__struma__thyromegaly  abnormally enlarged thyroid gland; can result from under-production or over-production of hormone or from a deficiency of iodine in the diet
  subtype:  #sandfly_fever__sandflyfever__pappataci_fever__phlebotomus  a mild viral disease transmitted by the bite of the sand fly Phlebotomus papatasii
  subtype:  #skin_disease__disease_of_the_skin__skin_disorder__skin_problem__skin_condition  a disease affecting the skin
     subtype:  #acantholysis  a breakdown of a cell layer in the epidermis (as in pemphigus)
     subtype:  #acanthosis  an abnormal but benign thickening of the prickle-cell layer of the skin (as in psoriasis)
     subtype:  #acanthosis_nigricans__keratosis_nigricans__keratosisnigrican  a skin disease characterized by dark wart-like patches in the body folds; can be benign or malignant
     subtype:  #acne  an inflammatory disease involving the sebaceous glands of the skin; characterized by papules or pustules or comedones
     subtype:  #dermatosis  disorder involving lesions or eruptions of the skin (in which there is usually no inflammation)
        subtype:  #pityriasis  any of several skin disorders characterized by shedding dry flakes of skin
           subtype:  #dandruff.pityriasis  a condition in which white scales of dead skin are shed by the scalp
           subtype:  #pityriasis_alba  common form of pityriasis (usually in children or young adults) characterized by round patches of depigmentation
           subtype:  #pityriasis_rosea  pityriasis in which an itchy rash develops over the trunk and extremities
     subtype:  #eczema  generic term for inflammatory conditions of the skin; particularly with vesiculation in the acute stages
        subtype:  #dermatitis  inflammation of the skin; skin becomes itchy and may develop blisters
           subtype:  #actinic_dermatitis  dermatitis caused exposure to sunlight
           subtype:  #atopic_dermatitis__atopic_eczema  dermatitis characterized by atopy
           subtype:  #contact_dermatitis  a delayed type of allergic reaction of the skin resulting from skin contact with a specific allergen (such as poison ivy)
              subtype:  #bubble_gum_dermatitis  an allergic contact dermatitis developed around the lips of children who chew bubble gum
              subtype:  #Rhus_dermatitis  contact dermatitis resulting from contact with plants of the genus Toxicodendron
                 subtype:  #poison_ivy  dermatitis resulting from contact with the poison ivy plant
                 subtype:  #poison_oak  dermatitis resulting from contact with a poison oak plant
                 subtype:  #poison_sumac  dermatitis resulting from contact with a poison sumac plant
           subtype:  #cradle_cap  a dermatitis of the scalp that is common in infants
           subtype:  #diaper_rash__diaper_dermatitis  dermatitis of the thighs and buttocks of infants; supposedly caused by ammonia in the urine in the child's diapers
           subtype:  #hypericism  a severe dermatitis of herbivorous domestic animals attributable to photosensitivity from eating Saint John's wort
           subtype:  #neurodermatitis__neurodermatiti  dermatitis in which localized areas (especially the forearms or back of the neck or outer part of the ankle) itch persistently; cause is unknown
           subtype:  #schistosome_dermatitis__swimmer's_itch__swimmer'sitch  a sensitization reaction to repeated invasion of the skin by cercariae of schistosomes (human or animal)
           subtype:  #seborrheic_dermatitis__seborrheic_eczema  a chronic skin disease associated with seborrhea and greasy scales on the scalp or eyelids or other parts of the skin
        subtype:  #allergic_eczema  eczema caused by an allergic reaction
           subtype:  #baker's_eczema__baker'seczema  allergic eczema caused by flour or other ingredients handled by bakers
        subtype:  #eczema_herpeticum  eczema characterized by a feverish condition and widespread eruption of vesicles; most common in children
        subtype:  #lichtenoid_eczema__chronic_eczema__chroniceczema__eczema_hypertrophicum  eczema characterized by thickening of the skin with accentuated skin lines
     subtype:  #erythroderma  any skin disorder involving abnormal redness
        subtype:  #erythema  abnormal redness of the skin resulting from dilation of blood vessels (as in sunburn or inflammation)
           subtype:  #erythema_multiforme  a red rash caused by hypersensitivity to a drug or disease or other allergen
           subtype:  #erythema_nodosum  skin condition characterized by tender red nodules on the shins and legs
              subtype:  #erythema_nodosum_leprosum__ENL  an inflammatory complication of leprosy that results in painful skin lesions on the arms and legs and face
           subtype:  #hickey__love_bite  a temporary red mark on a person's skin resulting from kissing or sucking by their lover
           subtype:  #erythema_solare__sunburn  redness of the skin caused by exposure to the rays of the sun
           subtype:  #windburn  redness and irritation of the skin caused by exposure to high-velocity wind
        subtype:  #flare.erythroderma  reddening of the skin spreading outward from a focus of infection or irritation
     subtype:  #furunculosis  acute skin disease characterized by the presence of many furuncles
     subtype:  #impetigo  a very contagious infection of the skin; common in children; localized redness develops into small blisters that gradually crust and erode
     subtype:  #jungle_rot  skin disorder induced by a tropical climate
     subtype:  #keratoderma  any skin disorder consisting of a growth that appears horny
     subtype:  #keratonosis  any abnormal condition of the outer skin (epidermis)
     subtype:  #keratosis__keratosi  a skin condition marked by an overgrowth of layers of horny skin
        subtype:  #actinic_keratosis__actinickeratosi  an overgrowth of skin layers resulting from extended exposure to the sun
        subtype:  #keratosis_blennorrhagica__keratosisblennorrhagica__keratoderma_blennorrhagica__keratodermablennorrhagica  skin disease characterized by a scaly rash on the palms and soles; associated with Reiter's syndrome
        subtype:  #keratosis_follicularis__Darier's_disease  a rare hereditary condition marked by dark crusted patches (sometimes containing pus)
        subtype:  #keratosis_pilaris__keratosispilari  keratosis characterized by hard conical elevations in the openings of sebaceous glands (especially of arms and thighs)
        subtype:  #seborrheic_keratosis  a skin condition characterized by circumscribed wartlike lesions that can be itchy and covered with a greasy crust
     subtype:  #leukoderma  a congenital skin condition characterized by spots or bands of unpigmented skin
     subtype:  #lichen.skin_disease  any of several eruptive skin diseases characterized by hard thick lesions grouped together and resembling lichens growing on rocks
        subtype:  #lichen_planus__lichen_ruber_planus  an eruption of shiny flat-topped purplish (usually itchy) papules on the wrist and forearms and thighs
     subtype:  #livedo  skin disorder characterized by patchy bluish discolorations on the skin
     subtype:  #lupus__lupu  any of several forms of ulcerative skin disease
        subtype:  #lupus_vulgaris  tuberculosis of the skin; appears first on the face and heals slowly leaving deep scars
        subtype:  #discoid_lupus_erythematosus__DLE  a chronic skin disease occurring primarily in women between the ages of 20 and 40; characterized by an eruption of red lesions over the cheeks and bridge of the nose
        subtype:  #lupus_erythematosus__lupuserythematosu__LE  a chronic inflammatory collagen disease affecting connective tissue (skin or joints)
        subtype:  #systemic_lupus_erythematosus__SLE__disseminated_lupus_erythematosus  an inflammatory disease of connective tissue with variable features including fever and weakness and fatigability and joint pains and skin lesions on the face or neck or arms
     subtype:  #melanosis__melanosi__melanism  a condition characterized by abnormal deposits of melanin (especially in the skin)
     subtype:  #molluscum  any skin disease characterized by soft pulpy nodules
        subtype:  #molluscum_contagiosum__molluscumcontagiosum  a virus disease of the skin marked by round white swellings; transmitted from person to person (most often in children or in adults with impaired immune function)
     subtype:  #necrobiosis_lipoidica_diabeticorum__necrobiosislipoidicadiabeticorum__necrobiosis_lipoidica__necrobiosislipoidica  skin disease marked by thin shiny patches (especially on the legs); often associated with diabetes mellitus
     subtype:  #pemphigus__pemphigu  a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane
     subtype:  #prurigo  chronic inflammatory disease of the skin characterized by blister capped papules and intense itching
     subtype:  #psoriasis__psoriasi  a chronic skin disease characterized by dry red patches covered with scales; occurs especially on the scalp and ears and genitalia and the skin over bony prominences
     subtype:  #rhagades  cracks or fissures in the skin (especially around the mouth or anus)
     subtype:  #Saint_Anthony's_fire  any of several inflammatory or gangrenous skin conditions
        subtype:  #erysipelas  an acute streptococcal infection characterized by deep-red inflammation of the skin and mucous membranes
     subtype:  #seborrhea  a condition in which overactivity of the sebaceous glands causes the skin to become oily
     subtype:  #vitiligo  an acquired skin disease characterized by patches of unpigmented skin (often surrounded by a heavily pigmented border)
     subtype:  #xanthoma  a skin problem marked by the development (on the eyelids and neck and back) of irregular yellow nodules; sometimes attributable to disturbances of cholesterol metabolism
        subtype:  #xanthelasma  xanthoma of the eyelids; occurs chiefly in the elderly
        subtype:  #xanthoma_disseminatum  rare chronic xanthoma of adults n which orange or brownish papules develop on many surfaces of the body
        subtype:  #xanthomatosis__xanthomatosi__xanthoma_multiplex__cholesterosis_cutis__cholesterosiscuti__lipid_granulomatosis__lipoid_granulomatosis  widespread xanthomas (especially on elbows and knees); often associated with a disorder of lipid metabolism
     subtype:  #xanthosis__xanthosi  an abnormal yellow discoloration of the skin
  subtype:  #malignancy__malignance  (medical) a malignant state; progressive and resistant to treatment and tending to cause death
     subtype:  #malignant_tumor__malignanttumor__malignant_neoplasm__malignantneoplasm__metastatic_tumor  a tumor that is malignant and tends to spread to other parts of the body
        subtype:  #carcinosarcoma  a malignant neoplasm composed of carcinoma and sarcoma extensively intermixed
        subtype:  #cancer__malignant_neoplastic_disease  any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream
           subtype:  #lymphoma  a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer
              subtype:  #Hodgkin's_disease  a malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver
           subtype:  #carcinoma  any malignant tumor derived from epithelial tissue; one of the four major types of cancer
              subtype:  #liver_cancer__livercancer__cancer_of_the_liver  malignant neoplastic disease of the liver usually occurring as a metastasis from another cancer; symptoms include loss of appetite and weakness and bloating and jaundice and upper abdominal discomfort
              subtype:  #adenocarcinoma__glandular_cancer__glandularcancer__glandular_carcinoma__glandularcarcinoma  malignant tumor originating in glandular epithelium
                 subtype:  #prostate_cancer__prostatic_adenocarcinoma__prostaticadenocarcinoma  cancer of the prostate gland
              subtype:  #breast_cancer  cancer of the breast; one of the most common malignancies in women in the US
              subtype:  #carcinoma_in_situ__preinvasive_cancer__preinvasivecancer  a cluster of malignant cells that has not yet invaded the deeper epithelial tissue or spread to other parts of the body
              subtype:  #colon_cancer__coloncancer  a malignant tumor of the colon; early symptom is bloody stools
              subtype:  #embryonal_carcinoma  malignant neoplasm of the testis
              subtype:  #endometrial_carcinoma__endometrialcarcinoma__endometrial_cancer__endometrialcancer  cancer of the uterine lining
              subtype:  #malignant_hepatoma__malignanthepatoma__hepatoma__hepatocarcinoma__hepatocellular_carcinoma  carcinoma of the liver
              subtype:  #lung_cancer  carcinoma of the lungs; one of the commonest forms of cancer
              subtype:  #mesothelioma  a rare form of carcinoma of the mesothelium lining lungs or abdomen or heart; usually associated with exposure to asbestos dust
              subtype:  #oat_cell_carcinoma__small_cell_carcinoma  highly malignant carcinoma composed of small round or egg-shaped cells with little cytoplasm; lung cancers are frequently oat cell carcinomas
              subtype:  #oral_cancer  malignant neoplasm of the lips of mouth; most common in men over the age of 60
              subtype:  #pancreatic_cancer  cancer of the pancreas
              subtype:  #seminoma__testicular_cancer  malignant tumor of the testis; usually occurring in older men
              subtype:  #skin_cancer  a malignant neoplasm of the skin
                 subtype:  #cancroid__squamous_cell_carcinoma  the most common form of skin cancer
                 subtype:  #epithelioma  a malignant tumor of the epithelial tissue
                 subtype:  #malignant_melanoma__malignantmelanoma__melanoma  any of several malignant neoplasms (usually of the skin) consisting of melanocytes
              subtype:  #trophoblastic_cancer__trophoblasticcancer  malignant neoplasm of the uterus derived from the epithelium of the chorion
           subtype:  #leukemia__leukaemia__cancer_of_the_blood  malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer
              subtype:  #acute_leukemia__acuteleukemia  rapidly progressing leukemia
                 subtype:  #acute_lymphocytic_leukemia__acutelymphocyticleukemia__acute_lymphoblastic_leukemia__acutelymphoblasticleukemia  acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children
                 subtype:  #acute_myelocytic_leukemia__acute_myeloid_leukemia__acutemyeloidleukemia  acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults
              subtype:  #chronic_leukemia__chronicleukemia  slowly progressing leukemia
                 subtype:  #chronic_lymphocytic_leukemia__chroniclymphocyticleukemia  chronic leukemia characterized by lymphoblast-like cells; more common in older men
                 subtype:  #chronic_myelocytic_leukemia__myeloid_leukemia__myeloidleukemia  chronic leukemia characterized by granular leukocytes; more common in older people
              subtype:  #lymphocytic_leukemia__lymphocyticleukemia  leukemia characterized by enlargement of lymphoid tissues and lymphocytic cells in the circulating blood
                 subtype:  #lymphoblastic_leukemia__lymphoblasticleukemia  a form of lymphocytic leukemia in which the abnormal cells in the circulating blood are almost totally lymphoblasts
              subtype:  #monocytic_leukemia__monocyticleukemia__monocytic_lukaemia__monocyticlukaemia__monoblastic_leukemia__monoblasticleukemia__monoblstic_leukaemia__histiocytic_leukemia__histiocyticleukemia__histiocytic_leukaemia__histiocyticleukaemia  leukemia characterized by the proliferation of monocytes and monoblasts in the blood
              subtype:  #myeloblastic_leukemia  a malignant neoplasm of blood-forming tissues; characterized by numerous myeloblasts in the blood stream
              subtype:  #myelocytic_leukemia__granulocytic_leukemia  a malignant neoplasm of blood-forming tissues; marked by proliferation of myelocytes and their presence in the blood
                 subtype:  #acute_myelocytic_leukemia__acute_myeloid_leukemia__acutemyeloidleukemia  acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults
                 subtype:  #chronic_myelocytic_leukemia__myeloid_leukemia__myeloidleukemia  chronic leukemia characterized by granular leukocytes; more common in older people
           subtype:  #sarcoma  a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer
              subtype:  #chondrosarcoma  a malignant neoplasm of cartilage cells
              subtype:  #Ewing's_sarcoma__Ewing's_tumor__Ewing's_tumour__endothelial_myeloma__endothelialmyeloma  malignant tumor in bone marrow (usually in the pelvis or in long bones)
              subtype:  #Kaposi's_sarcoma  a sarcoma that starts with purplish spots on the feet and legs and spreads from the skin to lymph nodes and internal organs; a common manifestation of AIDS; "until 1980 Kaposi's sarcoma occurred almost exclusively with Jewish or Italian or black men"
              subtype:  #leiomyosarcoma  sarcoma of smooth muscle; occurs most often digestive tract or uterus or bladder or prostate
              subtype:  #liposarcoma  sarcoma of fat cells
              subtype:  #myosarcoma  sarcoma of muscle tissue
              subtype:  #neurosarcoma__malignant_neuroma__malignantneuroma  a malignant neoplasm of nerve tissue and fibrous tissue and connective tissue
              subtype:  #osteosarcoma__osteogenic_sarcoma  malignant bone tumor; most common in children and young adults where it tends to affect the femur
              subtype:  #rhabdomyosarcoma__rhabdosrcoma  a highly malignant neoplasm derived from striated muscle
                 subtype:  #embryonal_rhabdomyosarcoma__embryonalrhabdomyosarcoma__embryonal_rhabdosarcoma__embryonalrhabdosarcoma  form of rhabdomyosarcoma occurring mainly in infants and children
                 subtype:  #alveolar_rhabdomyosarcoma__alveolar_rhabdosarcoma  form of rhabdomyosarcoma occuring mainly in adolescents and young adults
                 subtype:  #pleomorphic_rhabdomyosarcoma__pleomorphicrhabdomyosarcoma__pleomorphic_rhabdosarcoma  form of rhabdomyosarcoma that affects limb muscles of older adults
              subtype:  #Wilms'_tumor__Wilms_tumour__adenomyosarcoma__nephroblastoma__embryoma_of_the_kidney  malignant renal tumor of young children characterized by hypertension and blood in the urine and the presence of a palpable mass
        subtype:  #retinoblastoma  malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
  subtype:  #eye_disease__eyedisease  any disease of the eye
     subtype:  #glaucoma  increased pressure in the eyeball due to obstruction of the outflow of aqueous humor; damages the optic disc and impairs vision (sometimes progressing to blindness)
        subtype:  #acute_glaucoma__acuteglaucoma__angle-closure_glaucoma__angleclosureglaucoma  glaucoma in which the iris blocks the outflow of aqueous humor
        subtype:  #chronic_glaucoma__chronicglaucoma__open-angle_glaucoma  glaucoma caused by blockage of the canal of Schlemm; produces gradual loss of peripheral vision
     subtype:  #keratonosus__keratonosu  any disease of the cornea
     subtype:  #trachoma  a chronic contagious viral disease marked by inflammation of the conjunctiva and cornea of the eye and the formation of scar tissue
     subtype:  #leukoma  eye disease consisting of an opaque white spot on the cornea
     subtype:  #cataract  clouding of the natural lens of the eye
  subtype:  #animal_disease  a disease that typically does not affect human beings
     subtype:  #warble  a lumpy abscess under the hide of domestic mammals caused by larvae of a botfly or warble fly
     subtype:  #anaplasmosis  a disease of cattle that is transmitted by cattle ticks; similar to Texas fever
     subtype:  #brooder_pneumonia__brooderpneumonia__aspergillosis__aspergillosi  severe respiratory disease of birds that takes the form of an acute rapidly fatal pneumonia in young chickens and turkeys
     subtype:  #bighead  any of various diseases of animals characterized by edema of the head and neck
     subtype:  #bull_nose  a disease of pigs resulting in swelling of the snout
     subtype:  #canine_chorea__chorea  chorea in dogs
     subtype:  #costiasis__costiasi  a fatal disease of fresh-water fish caused by a flagellated protozoan invading the skin
     subtype:  #cowpox__vaccinia  a viral disease of cattle causing a mild skin disease affecting the udder; formerly used to inoculate humans against smallpox
     subtype:  #creeps.animal_disease  a disease of cattle and sheep attributed to a dietary deficiency; characterized by anemia and softening of the bones and a slow stiff gait
     subtype:  #hemorrhagic_septicemia__hemorrhagicsepticemia__pasteurellosis  an acute infectious disease characterized by pneumonia and blood infection
     subtype:  #fowl_cholera  an acute diarrheal disease (especially of chickens) caused by the microorganism that causes hemorrhagic septicemia
     subtype:  #fowl_pest  an acute viral disease of domestic fowl; characterized by refusal to each and high temperature and discoloration of the comb
     subtype:  #hog_cholera  highly infectious virus disease of swine
     subtype:  #distemper  any of various infectious diseases of animals
        subtype:  #canine_distemper  a viral disease of young dogs characterized by high fever and respiratory inflammation
        subtype:  #equine_distemper__strangles__strangle  an acute bacterial disease of horses characterized by inflammation of the mucous membranes
     subtype:  #enterotoxemia  a disease of cattle and sheep that is attributed to toxins absorbed from the intestines
     subtype:  #foot-and-mouth_disease__hoof-and-mouth_disease  acute contagious disease of cloven-footed animals marked by ulcers in the mouth and around the hoofs
     subtype:  #foot_rot  contagious degenerative infection of the feet of hoofed animals (especially cattle and sheep)
     subtype:  #black_disease__blackdisease__sheep_rot__sheeprot__liver_rot__liverrot__distomatosis  a disease of the liver (especially in sheep and cattle) caused by liver flukes and their by-products
     subtype:  #heaves__broken_wind  a chronic emphysema of the horse that causes difficult expiration and heaving of the flanks
     subtype:  #red_water__redwater  a disease of cattle; characterized by hematuria
     subtype:  #rhinotracheitis__rhinotracheiti  an respiratory infection of the nose and throat in cattle
     subtype:  #rinderpest__cattle_plague  an acute infectious viral disease of cattle (usually fatal); characterized by fever and diarrhea and inflammation of mucous membranes
     subtype:  #scours  diarrhea in livestock
     subtype:  #bovine_spongiform_encephalitis__BSE__mad_cow_disease__madcowdisease  a fatal disease of cattle that affects the central nervous system; causes staggering and agitation
     subtype:  #scrapie  a fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system
     subtype:  #shipping_fever__shipping_pneumonia  a deadly form of septicemia in cattle and sheep; involves high fever and pneumonia; contracted under conditions of exposure or exhaustion (as often happens when the animals are shipped to market)
     subtype:  #spavin  a swelling of the hock joint of a horse; resulting in lameness
        subtype:  #blood_spavin__bloodspavin  spavin caused by distension of the veins
        subtype:  #bog_spavin__bogspavin  spavin caused by collection of fluids
        subtype:  #bone_spavin  spavin caused by a bony growth
     subtype:  #loco_disease__locoism  a disease of livestock caused by locoweed poisoning; characterized by weakness and lack of coordination and trembling and partial paralysis
     subtype:  #mange  an persistent and contagious disease of the skin causing inflammation and itching and loss of hair; affects domestic animals (and sometimes people)
     subtype:  #moon_blindness__mooneye  recurrent eye inflammation in horses; sometimes resulting in blindness
     subtype:  #murrain  any plaguelike disease of domestic animals
     subtype:  #myxomatosis__myxomatosi  a viral disease (usually fatal) of rabbits
     subtype:  #Newcastle_disease  disease of domestic fowl and other birds
     subtype:  #pip.animal_disease  a disease of poultry
     subtype:  #psittacosis__psittacosi__parrot_disease  infectious disease of birds
     subtype:  #pullorum_disease__bacillary_white_diarrhea__bacillarywhitediarrhea__bacillary_white_diarrhoea__bacillarywhitediarrhoea  a serious bacterial disease of young chickens
     subtype:  #saddle_sore.animal_disease__saddlesore__gall  an open sore on the back of a horse caused by ill-fitting or badly adjusted saddle
     subtype:  #sand_crack  a fissure in the wall of a horse's hoof often causing lameness
        subtype:  #toe_crack__toecrack  a crack on the forepart of a horse's hindfoot
        subtype:  #quarter_crack__quartercrack  a crack on the inside of a horse's forefoot
     subtype:  #sweating_sickness  a disease of cattle (especially calves)
     subtype:  #Texas_fever  an infectious disease of cattle transmitted by the cattle tick
     subtype:  #trembles__milk_sickness  disease of livestock and especially cattle poisoned by eating certain kinds of snakeroot
     subtype:  #zoonosis  an animal disease that can be transmitted to humans
        subtype:  #actinomycosis__actinomycosi  disease of cattle that can be transmitted to humans; results from infection with actinomycetes; characterized by hard swellings that exude pus through long sinuses
           subtype:  #cervicofacial_actinomycosis__cervicofacialactinomycosi__lumpy_jaw__lumpyjaw  the commonest and least severe form of actinomycosis; affects the face and neck regions
           subtype:  #thoracic_actinomycosis  a serious form of actinomycosis that affects the chest
           subtype:  #abdominal_actinomycosis__abdominalactinomycosi  a serious form of actinomycosis that affects the abdomen
        subtype:  #anthrax__splenic_fever__splenicfever  a highly infectious animal disease (especially cattle and sheep); it can be transmitted to people
        subtype:  #brucellosis__contagious_abortion__Bang's_disease  an infectious disease of domestic animals often resulting in spontaneous abortion; transmittable to human beings
        subtype:  #glanders  a destructive and contagious bacterial disease of horses that can be transmitted to humans
        subtype:  #Lyme_disease__Lyme_arthritis  an acute inflammatory disease characterized by a rash with joint swelling and fever; caused by bacteria carried by the bite of a deer tick
        subtype:  #Marburg_disease__Marburg-ebola_disease__green_monkey_disease  a viral disease of green monkeys; when transmitted to humans it causes serious or fatal illness
        subtype:  #rabies__hydrophobia__madness  an acute viral disease of the nervous system of warm-blooded animals (usually transmitted by the bite of a rabid animal); rabies is fatal if the virus reaches the brain
        subtype:  #swamp_fever__swampfever__leptospirosis__leptospirosi  an infectious disease cause by leptospira and transmitted to humans from domestic animals; characterized by jaundice and fever
           subtype:  #canicola_fever  an acute feverish disease in people and in dogs marked by gastroenteritis and mild jaundice
           subtype:  #Weil's_disease  a severe form of leptospirosis in human beings
        subtype:  #tularemia__tularaemia__rabbit_fever__deer_fly_fever__yatobyo  disease of rodents (especially rabbits and squirrels) and sometimes transmitted to humans by ticks or flies or by handling infected animals
  subtype:  #plant_disease__plantdisease  a disease that affects plants
     subtype:  #blight  any plant disease resulting in withering without rotting
        subtype:  #alder_blight__alderblight  a disease of alders caused by the woolly alder aphid (a plant louse)
        subtype:  #apple_blight__appleblight__apple_canker__applecanker  a disease of apple trees
        subtype:  #beet_blight  a disease of beet plants
        subtype:  #blister_blight__blisterblight  a disease of tea plants
        subtype:  #blister_blight.blight__blisterblight  a disease of Scotch pines
        subtype:  #cane_blight  a disease affecting the canes of various bush fruits (e.g., raspberries or currants)
        subtype:  #chestnut_blight__chestnut_canker__chestnut-bark_disease  a disease of American chestnut trees
        subtype:  #coffee_blight  a blight affecting the coffee plant
        subtype:  #collar_blight  a disease affecting the trunks of pear and apple trees
        subtype:  #halo_spot__halo_blight__bean_blight  a blight of bean plants
        subtype:  #halo_blight  a blight affecting the leaves of oats and other grasses
        subtype:  #head_blight  a blight of the heads of cereals
           subtype:  #wheat_scab__wheatscab  a disease of the heads of wheat plants
        subtype:  #late_blight  blight in which symptoms appear late in the growing season especially a disease of solanaceous plants caused by the fungus Phytophthora infestans
           subtype:  #celery_blight  a fungous leaf spot disease of the celery plant
        subtype:  #leaf_blight  any blight causing a browning and falling of the leaves of a plant
           subtype:  #fire_blight__pear_blight  a disease blackening the leaves of pear and apple trees
              subtype:  #blight_canker  a phase of fire blight in which cankers appear
           subtype:  #needle_blight__needle_cast__leaf_cast  a disease of conifers causing the needles to fall
        subtype:  #peach_blight__peachblight  a disease of trees bearing drupes
        subtype:  #potato_blight__potato_mold__potato_disease__potato_mildew__potato_murrain  a blight of potatoes
        subtype:  #rim_blight__rimblight  a disease of tea plants
        subtype:  #spinach_blight__spinachblight  a disease of spinach plants
        subtype:  #spur_blight  a disease of raspberries
        subtype:  #stem_blight  a fungous blight attacking the stems of plants
        subtype:  #stripe_blight  a disease of oats
        subtype:  #thread_blight  a disease of tropical woody plants(cocoa or tea or citrus)
        subtype:  #tomato_blight__tomato_yellows  a disease of tomato plants
        subtype:  #twig_blight  a disease of the ends of twigs of woody plants
        subtype:  #walnut_blight  a disease of English walnut trees
     subtype:  #rust  a reddish-brown discoloration of leaves and stems caused by a rust fungus
        subtype:  #white_pine_blister_rust__whitepineblisterrust__blister_rust__blisterrust__white-pine_rust__whitepinerust  any of several diseases of pines caused by rust fungi of the genus Cronartium and marked by destructive invasion of bark and sapwood and producing blisters externally
     subtype:  #blackheart  any of various diseases in which the central tissues blacken
     subtype:  #black_knot__blackknot  disease of plum and cherry trees characterized by black excrescences on the branches
     subtype:  #black_rot__blackrot  a fungous disease causing darkening and decay of the leaves of fruits and vegetables
     subtype:  #black_spot__blackspot  any of several fungous diseases of plants that produce small black spots on the plant
     subtype:  #bottom_rot  fungous disease of lettuce that first rots lower leaves and spreads upward
     subtype:  #brown_rot__brownrot  any of certain fungous diseases of plants characterized by browning and decay of tissues
        subtype:  #brown_rot_gummosis__gummosis  disease of citrus trees caused by the fungus Phytophthora citrophthora
        subtype:  #ring_rot__ring_disease__tobacco_wilt__tobaccowilt  disease of tomatoes and potatoes and tobacco etc caused by the bacterium Pseudomonas solanacearum
     subtype:  #gummosis  pathological production of gummy exudates in citrus and various stone-fruit trees
     subtype:  #cotton_ball  a fungus disease of cranberries
     subtype:  #crown_gall__crowngall  a bacterial disease of plants (especially pome and stone fruits and grapes and roses) which forms excrescences on the stem near the ground
        subtype:  #hairy_root__hairyroot  a phase of crown gall (especially in apples) during which there is abnormal development of fine fibrous roots
     subtype:  #crown_wart__crownwart  a fungous disease of alfalfa which forms white excrescences at the base of the stem
     subtype:  #damping_off__dampingoff  a plant disease caused by a fungus; diseased condition of seedlings in excessive moisture
     subtype:  #dieback  a disease of plants characterized by the gradual dying of the young shoots starting at the tips and progressing to the larger branches
     subtype:  #dry_rot.plant_disease__dryrot  a crumbling and drying of timber or bulbs or potatoes or fruit caused by a fungus
     subtype:  #heartrot  any plant disease in which the central part of a plant rots (especially in trees)
     subtype:  #mosaic.plant_disease  viral disease in solanaceous plants (tomatoes; potatoes; tobacco) resulting in mottling and often shriveling of the leaves
        subtype:  #potato_mosaic  a disease of the leaves of potato plants
        subtype:  #tobacco_mosaic__tobaccomosaic  a plant disease causing discoloration of the leaves of tobacco plants
     subtype:  #rhizoctinia_disease__rhizoctiniadisease  disease caused by rhizoctinia or fungi of Pellicularia and Corticium
        subtype:  #little_potato__rosette__russet_scab__stem_canker  rhizoctinia disease of potatoes
     subtype:  #pink_disease  serious bark disease of many tropical crop trees (coffee; citrus; rubber); branches have a covering of pink hyphae
     subtype:  #potato_wart  fungous disease causing dark warty spongy excrescences in the eyes of potato tubers
     subtype:  #root_rot  disease characterized by root decay; caused by various fungi
     subtype:  #sweet-potato_ring_rot  disease of sweet potatoes in which roots are girdled by rings of dry rot
     subtype:  #sclerotium_disease__sclerotium_rot  plant disease cause by fungi of the genus Sclerotium; also one in which sclerotia are formed
     subtype:  #Dutch_elm_disease  disease of elms caused by a fungus
     subtype:  #ergot  a plant disease caused by the ergot fungus
     subtype:  #foot_rot.plant_disease__footrot  plant disease in which the stem or trunk rots at the base
     subtype:  #pinkroot  a fungal disease of onions
     subtype:  #wilt_disease__wilt  any plant disease characterized by drooping and shriveling; usually caused by parasites attacking the roots
        subtype:  #granville_wilt__granvillewilt  a bacterial wilt of tobacco plants
        subtype:  #fusarium_wilt  caused by fungi of the genus Fusarium
        subtype:  #verticilliosis  caused by soil-borne fungi of the genus Verticillium
     subtype:  #smut  destructive diseases of plants (especially cereal grasses) caused by fungi that produce black powdery masses of spores
        subtype:  #loose_smut.smut__loosesmut  disease of grains; the entire head is a dusty mass of spores
        subtype:  #stinking_smut__bunt  disease of wheat characterized by replacement of the grains with greasy masses of smelly smut spores
        subtype:  #flag_smut  smut affecting leaves and stems of cereals and other grasses
        subtype:  #green_smut__greensmut__false_smut__falsesmut  disease of rice; grains covered by a green powder consisting of conidia
     subtype:  #soft_rot  mushy or slimy decay of plants caused by bacteria or fungi
        subtype:  #leak.soft_rot  soft watery rot in fruits and vegetables caused by fungi
     subtype:  #yellow_dwarf  any of several virus diseases of plants characterized by stunting and yellowing of the leaves
        subtype:  #yellow_dwarf_of_potato__potato_yellow_dwarf  the yellow dwarf disease of potato plants
        subtype:  #onion_yellow_dwarf  the yellow dwarf disease of onion plants
     subtype:  #yellow_spot  any of several fungous or viral diseases characterized by yellow spotting on the leaves
        subtype:  #tomato_streak  disease of a wide range of plants (tomatoes; potatoes; peas) resulting from a mixed infection of potato and tomato mosaic
  subtype:  #ozena__ozaena  a chronic disease of the nose characterized by a foul-smelling nasal discharge and atrophy of nasal structures
  subtype:  #filariasis  a disease caused by nematodes in the blood or tissues of the body causing blockage of lymphatic vessels

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