#autoimmune_disease__autoimmune_disorder any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
supertype: #disease an impairment of health or a condition of abnormal functioning
part: #autoimmunity
subtype: #Type_I_diabetes__insulin-dependent_diabetes_mellitus__IDDM__juvenile-onset_diabetes__juvenile_diabetes__growth-onset_diabetes__ketosis-prone_diabetes__ketoacidosis-prone_diabetes__autoimmune_diabetes severe diabetes mellitus with an early onset; characterized by polyuria and excessive thirst and increased appetite and weight loss and episodic ketoacidosis; diet and insulin injections are required to control the disease
subtype: #rheumatoid_arthritis__atrophic_arthritis__rheumatism a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
subtype: #psoriatic_arthritis a form of rheumatoid arthritis usually affecting fingers and toes and associated with psoriasis
subtype: #Still's_disease__juvenile_rheumatoid_arthritis a form of rheumatoid arthritis that affects children; large joints become inflamed and bone growth may be retarded
subtype: #ankylosing_spondylitis__Marie-Strumpell_disease__rheumatoid_spondylitis a chronic form of spondylitis primarily in males and marked by impaired mobility of the spine; sometimes leads to ankylosis
subtype: #discoid_lupus_erythematosus__DLE a chronic skin disease occurring primarily in women between the ages of 20 and 40; characterized by an eruption of red lesions over the cheeks and bridge of the nose
subtype: #Hashimoto's_disease autoimmune disorder of the thyroid gland; most common in middle-aged women
subtype: #lupus_erythematosus__lupuserythematosu__LE a chronic inflammatory collagen disease affecting connective tissue (skin or joints)
subtype: #scleroderma__dermatosclerosis an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin
subtype: #morphea localized scleroderma
subtype: #idiopathic_thrombocytopenic_purpura__thrombocytopenic_purpura__purpura_hemorrhagica__purpurahemorrhagica__Werlhof's_disease purpura associated with a reduction in circulating blood platelets which can result from a variety of factors
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