#malignancy__malignance  (medical) a malignant state; progressive and resistant to treatment and tending to cause death
  supertype:  #disease  an impairment of health or a condition of abnormal functioning
  part:  #cancer_cell
  subtype:  #malignant_tumor__malignanttumor__malignant_neoplasm__malignantneoplasm__metastatic_tumor  a tumor that is malignant and tends to spread to other parts of the body
     subtype:  #carcinosarcoma  a malignant neoplasm composed of carcinoma and sarcoma extensively intermixed
     subtype:  #cancer__malignant_neoplastic_disease  any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream
        subtype:  #lymphoma  a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer
           subtype:  #Hodgkin's_disease  a malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver
        subtype:  #carcinoma  any malignant tumor derived from epithelial tissue; one of the four major types of cancer
           subtype:  #liver_cancer__livercancer__cancer_of_the_liver  malignant neoplastic disease of the liver usually occurring as a metastasis from another cancer; symptoms include loss of appetite and weakness and bloating and jaundice and upper abdominal discomfort
           subtype:  #adenocarcinoma__glandular_cancer__glandularcancer__glandular_carcinoma__glandularcarcinoma  malignant tumor originating in glandular epithelium
              subtype:  #prostate_cancer__prostatic_adenocarcinoma__prostaticadenocarcinoma  cancer of the prostate gland
           subtype:  #breast_cancer  cancer of the breast; one of the most common malignancies in women in the US
           subtype:  #carcinoma_in_situ__preinvasive_cancer__preinvasivecancer  a cluster of malignant cells that has not yet invaded the deeper epithelial tissue or spread to other parts of the body
           subtype:  #colon_cancer__coloncancer  a malignant tumor of the colon; early symptom is bloody stools
           subtype:  #embryonal_carcinoma  malignant neoplasm of the testis
           subtype:  #endometrial_carcinoma__endometrialcarcinoma__endometrial_cancer__endometrialcancer  cancer of the uterine lining
           subtype:  #malignant_hepatoma__malignanthepatoma__hepatoma__hepatocarcinoma__hepatocellular_carcinoma  carcinoma of the liver
           subtype:  #lung_cancer  carcinoma of the lungs; one of the commonest forms of cancer
           subtype:  #mesothelioma  a rare form of carcinoma of the mesothelium lining lungs or abdomen or heart; usually associated with exposure to asbestos dust
           subtype:  #oat_cell_carcinoma__small_cell_carcinoma  highly malignant carcinoma composed of small round or egg-shaped cells with little cytoplasm; lung cancers are frequently oat cell carcinomas
           subtype:  #oral_cancer  malignant neoplasm of the lips of mouth; most common in men over the age of 60
           subtype:  #pancreatic_cancer  cancer of the pancreas
           subtype:  #seminoma__testicular_cancer  malignant tumor of the testis; usually occurring in older men
           subtype:  #skin_cancer  a malignant neoplasm of the skin
              subtype:  #cancroid__squamous_cell_carcinoma  the most common form of skin cancer
              subtype:  #epithelioma  a malignant tumor of the epithelial tissue
              subtype:  #malignant_melanoma__malignantmelanoma__melanoma  any of several malignant neoplasms (usually of the skin) consisting of melanocytes
           subtype:  #trophoblastic_cancer__trophoblasticcancer  malignant neoplasm of the uterus derived from the epithelium of the chorion
        subtype:  #leukemia__leukaemia__cancer_of_the_blood  malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer
           subtype:  #acute_leukemia__acuteleukemia  rapidly progressing leukemia
              subtype:  #acute_lymphocytic_leukemia__acutelymphocyticleukemia__acute_lymphoblastic_leukemia__acutelymphoblasticleukemia  acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children
              subtype:  #acute_myelocytic_leukemia__acute_myeloid_leukemia__acutemyeloidleukemia  acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults
           subtype:  #chronic_leukemia__chronicleukemia  slowly progressing leukemia
              subtype:  #chronic_lymphocytic_leukemia__chroniclymphocyticleukemia  chronic leukemia characterized by lymphoblast-like cells; more common in older men
              subtype:  #chronic_myelocytic_leukemia__myeloid_leukemia__myeloidleukemia  chronic leukemia characterized by granular leukocytes; more common in older people
           subtype:  #lymphocytic_leukemia__lymphocyticleukemia  leukemia characterized by enlargement of lymphoid tissues and lymphocytic cells in the circulating blood
              subtype:  #lymphoblastic_leukemia__lymphoblasticleukemia  a form of lymphocytic leukemia in which the abnormal cells in the circulating blood are almost totally lymphoblasts
           subtype:  #monocytic_leukemia__monocyticleukemia__monocytic_lukaemia__monocyticlukaemia__monoblastic_leukemia__monoblasticleukemia__monoblstic_leukaemia__histiocytic_leukemia__histiocyticleukemia__histiocytic_leukaemia__histiocyticleukaemia  leukemia characterized by the proliferation of monocytes and monoblasts in the blood
           subtype:  #myeloblastic_leukemia  a malignant neoplasm of blood-forming tissues; characterized by numerous myeloblasts in the blood stream
           subtype:  #myelocytic_leukemia__granulocytic_leukemia  a malignant neoplasm of blood-forming tissues; marked by proliferation of myelocytes and their presence in the blood
              subtype:  #acute_myelocytic_leukemia__acute_myeloid_leukemia__acutemyeloidleukemia  acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults
              subtype:  #chronic_myelocytic_leukemia__myeloid_leukemia__myeloidleukemia  chronic leukemia characterized by granular leukocytes; more common in older people
        subtype:  #sarcoma  a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer
           subtype:  #chondrosarcoma  a malignant neoplasm of cartilage cells
           subtype:  #Ewing's_sarcoma__Ewing's_tumor__Ewing's_tumour__endothelial_myeloma__endothelialmyeloma  malignant tumor in bone marrow (usually in the pelvis or in long bones)
           subtype:  #Kaposi's_sarcoma  a sarcoma that starts with purplish spots on the feet and legs and spreads from the skin to lymph nodes and internal organs; a common manifestation of AIDS; "until 1980 Kaposi's sarcoma occurred almost exclusively with Jewish or Italian or black men"
           subtype:  #leiomyosarcoma  sarcoma of smooth muscle; occurs most often digestive tract or uterus or bladder or prostate
           subtype:  #liposarcoma  sarcoma of fat cells
           subtype:  #myosarcoma  sarcoma of muscle tissue
           subtype:  #neurosarcoma__malignant_neuroma__malignantneuroma  a malignant neoplasm of nerve tissue and fibrous tissue and connective tissue
           subtype:  #osteosarcoma__osteogenic_sarcoma  malignant bone tumor; most common in children and young adults where it tends to affect the femur
           subtype:  #rhabdomyosarcoma__rhabdosrcoma  a highly malignant neoplasm derived from striated muscle
              subtype:  #embryonal_rhabdomyosarcoma__embryonalrhabdomyosarcoma__embryonal_rhabdosarcoma__embryonalrhabdosarcoma  form of rhabdomyosarcoma occurring mainly in infants and children
              subtype:  #alveolar_rhabdomyosarcoma__alveolar_rhabdosarcoma  form of rhabdomyosarcoma occuring mainly in adolescents and young adults
              subtype:  #pleomorphic_rhabdomyosarcoma__pleomorphicrhabdomyosarcoma__pleomorphic_rhabdosarcoma  form of rhabdomyosarcoma that affects limb muscles of older adults
           subtype:  #Wilms'_tumor__Wilms_tumour__adenomyosarcoma__nephroblastoma__embryoma_of_the_kidney  malignant renal tumor of young children characterized by hypertension and blood in the urine and the presence of a palpable mass
     subtype:  #retinoblastoma  malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells

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